My laboratory specializes in the study and usage of molecular genetics on different life forms, especially those in plants.  The major thrust is to study and understand the workings and functions of DNA, genes and proteins and its usage in agriculture and medicine.  To achieve these ends, we have fabricated tools and developed techniques to expedite DNA delivery and transformation protocols for both plants and animals.  Along this approach, the use of computational biological techniques will also be implemented in the unraveling of the workings at molecular level.

In orchid research, we have produced the world's first transgenic glowing Dendrobium orchid flower, by successfully transforming the orchid cells with the firefly luciferase gene and  tracking its growth, development and gene expression.  We have also developed tissue-printing techniques for virus identification and eradication.  Physiological and molecular studies have shown that virus-free orchids have not only higher photosynthesis but also different translocation pattern from the diseased plants.  Also, we have identified DNA genetic markers for trait prediction like flower size and inflorescence length.

Another area of our research is in preventive medicine.  Here, we genetically alter plants to produce novel compounds with medicinal properties.  Our latest  breakthrough, which we have filed patent is the genetic engineering of  resveratrol producing red lettuce, for prevention against cancer and heart diseases. This was done by introducing the stilbene synthase gene into a red plant and diverting the precursors into resveratrol synthesis.  We are currently pursuing this area (preventive medicine) of research and are working on a number of compounds with medicinal properties.

On the educational front, which is another area of my interest, we have developed and patented a novel educational system called: Ability Driven Education (ADE) system.  This system integrates real life usage of knowledge into existing curriculum with pragmatic results.  The Orchid Hybridization Programme (OHP) is one such example and it is currently used in schools across Singapore. ADE system is currently practiced by other disciplines too.